Seq #2

Wednesday, April 2, 2008

1:30 PM-3:00 PM
Hilton Anatole Hotel Governors Lecture Hall, Symposium - Group/Division Sponsored

Challenges of Clinically Relevant Testing: Advanced Methods on the Horizon

Sponsored by: Dental Materials, ADA Standards Committee, NIDCR, NIST

Description: Problems associated with the long-term clinical performance of dental materials have persisted in spite of a significant research effort funded by NIDCR and other sources that has focused on developing new and improved materials. As an example, new materials that address the clinical longevity issues related to interfacial failure and secondary caries have yet to gained widespread clinical success despite decades of research. One significant reason impeding the research community’s ability to identify solutions to these persistent problems is the lack of clearly defined criteria for the materials properties related to longevity and function. Universally accepted standard test methods and reference materials would support academic and industrial researchers and in their development of new generations of dental materials. This movement is in accordance with the trend in the international standards community to develop methods that are performance based rather than material based. The need for new methods is also clearly described by the “Road Map to Performance Standards” developed by the American Dental Association Standards Committee on Dental Products (ADA SCDP). This symposium will provide an overview discussing the movement of dental standards towards performance based requirements using clinically relevant test methods, and the consequences and challenges this movement poses to standards developers, dental manufacturers, and regulators. Recently developed in vitro tests that are clinically relevant and provide spatial and temporal resolution will be highlighted. Specifically, real time monitoring of conversion dependence of stress as well as conversion dependence of polymerization shrinkage will be presented. For end-point characterization, the utility of combinatorial and high-throughput methods towards the development of integrated “test-suites” will be introduced. In addition, 3D imaging as a method to characterize various bulk and interfacial properties will be described. Finally, perspectives will be offered on the validation of in vitro testing and the interpretation of clinical study data.

Chairpersons: S. LIN-GIBSON and G.E. SCHUMACHER


0002	1:30 PM	Need for Performance-based Standards for Dentistry S.J. MEGREMIS, American Dental Association, Chicago, IL, USA
	1:50 PM	Real-time Monitoring of Conversion Dependence of Polymerization Shrinkage and Stress J.W. STANSBURY, University of Colorado School of Dentistry, Aurora, USA
	2:10 PM	Metrologies for Dental Materials: NIST's Role S. LIN-GIBSON, National Institute of Standards and Technology, Gaithersburg, MD, USA
	2:30 PM	Correlating and Interpreting in vitro Testing Results with in vivo Data J. LEMONS, University of Alabama, Birmingham, USA
	2:50 PM	Discussion

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