SESSION Seq #4: New Insights into Tooth and Craniofacial Development

Seq #4

Wednesday, April 2, 2008

1:30 PM-3:00 PM
Hilton Anatole Hotel Grand Ballroom E, Symposium - Group/Division Sponsored

New Insights into Tooth and Craniofacial Development

Sponsored by: Craniofacial Biology

Description: The purpose of this symposium is to introduce emerging concepts in tooth and craniofacial development, which will shape our current understanding of craniofacial biology. The keynote speaker for the group, Dr. Ophir Klein, will present his recent work on the molecular processes that regulate the behavior of dental stem cells, including their capacity to self-renew as well as to differentiate into the various cellular components of the tooth, and their application in the regeneration of dental tissues. Dr. Brad Amendt will describe the role of PITX2, a key homeodomain transcription factor in tooth and craniofacial development, in the regulation of Forkhead domain factors. Finally, Dr. Hiromi Yanagisawa will discuss the basic helix-loop-helix transcription factors Hand1 and Hand2 and their regulation of the development of midline mesenchyme. This symposium should be of broad interest to investigators at all stages of career development, with both clinicians and researchers benefiting from the diverse topics presented. Moreover, the areas of discussion will serve to set the stage for a discussion of potential strategies towards advancements of our understanding of craniofacial biology, as well as regenerative dental medicine. The educational objectives of this symposium are to: (1) provide an overview of classic and current current concepts in tooth and craniofacial development, (2) integrate novel signaling pathways involved in the patterning, determination, and fate of forming dental and craniofacial tissues, and (3) apply these concepts towards emerging areas in dental and craniofacial regeneration.

Chairperson: H. KAPADIA


0004	1:30 PM	Genetic Regulation of Stem Cell Progency in Mouse Incisor O. KLEIN, University of California, San Francisco, USA
	2:00 PM	Functional Characterization of Forkhead Domain Factors during Tooth Morphogenesis and its Regulation by PITX2 B.A. AMENDT, Texas A&M Health Science Center, Houston, USA
	2:30 PM	Genetic Dissection of Hand Genes during Craniofacial Developement in vivo H. YANAGISAWA, University of Texas Southwestern Medical Center, Dallas, USA

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