Different Pocket Rinsing Solutions during SRP - Clinical and Biochemical Results

Objectives: Different rinsing solutions for the application during scaling and root planing (SRP) are described in the literature. The aim of this prospective clinical controlled trial was to compare the influence of sodium chloride, chlorhexidine digluconate and povidone-iodine used as pocket rinsing solutions during SRP on clinical and biochemical results.

Methods: 51 adult volunteers with generalized moderate chronic periodontitis were treated by full mouth SRP using either 0.9% sodium chloride (group A, n=18), 0.12% chlorhexidine digluconate (B, n=17) or povidone-iodine (Betaisodona®, C=16) for pocket rinsing during SRP. PD, BOP and CAL were recorded in a 6-point measurement at baseline (0), after 3(1) and 12(2) months. Gingival crevicular fluid was collected at teeth with PD=4-6mm for quantitative biochemical analysis of polymorphonuclear elastase (EL) and myeloperoxidase (MPO) activities. Nonparametric tests were used for statistical analysis.

Results: The results were as follows: PD A0-3.03±0.43mm 1-2.85±0.57 2-2.67±0.33, B0-2.98±0.42 1-2.46±0.53 2-2.59±0.40, C0-2.98±0.34 1-2.60±0.23 2-2.54±0.33; BOP A0-33±17% 1-17±13 2-17±13, B0-30±20 1-14±13 2-13±10, C0-43±19 1-22±18 2-18±15; AL A0-3.32±0.73 1-3.09±0.71 2-3.11±0.67, B0-3.39±0.56 1-3.02±0.69 2-3.17±0.71, C0-3.26±0.40 1-2.87±0.38 2-2.88±0.57. PD was significantly reduced in all groups (p<0.001 – p=0.002), group 2 was better than group 1 after 3 months (p=0.041). BOP was significantly better in all groups (p<0.001 – p=0.002) but without significant differences between the groups. CAL was significantly better in all groups after 3 months, in group B and C also after 12 months (p<0.001, p=0.044) but without significant difference between the groups. The activities of EL and MPO were reduced in group A (5.69 vs. 29.54mU, p=0.013, 0.22 vs. 1.34mU, p=0.016).

Conclusions: Within the limits of the study one may conclude that there are no important differences between the applied solutions regarding the influence on clinical variables. Sodium chloride seems to have a better influence on the studied biochemical variables.