Baking Soda Dentifrices Enhance Plaque Removal by Brushing
L. VORWERK1, M.S. PUTT2, K.R. MILLEMAN2, P. SOPARKAR3, W. HOOPER1, A. GHASSEMI1, and A.E. WINSTON4, 1Church & Dwight Co., Inc, Princeton, NJ, USA, 2University Park Research Center, Fort Wayne, IN, USA, 3Forsyth Institute, Boston, MA, USA, 4R&D for Hire, East Brunswick, NJ, USA | Objective: To evaluate dentifrices containing baking soda for enhancing plaque removal in comparison to other dentifrices without baking soda. Method: Two independent, double-blind, single-brushing, crossover clinical studies were conducted using adult subjects with 24-hour plaque accumulation. Plaque was assessed by a different examiner in each study using the Turesky Modified Quigley-Hein Index before and after a single, 60-sec, supervised brushing with a manual toothbrush and dentifrice (1.5 gm). Washout periods of 3 days using a regular dentifrice separated each treatment. Dentifrice treatments were: Study #1 - 65% baking soda (BS) vs. NaF/Silica (FS); Study #2 - 20% BS vs. triclosan/copolymer (TC). Between-product comparisons were made using post-ANCOVA t-tests. Results: Pre-brushing mean plaque scores for both groups in each study were comparable. Whole-mouth, pre- to post-brushing plaque score reductions (Mean±SD) are summarized below: | N | 65% BS | 20% BS | FS | TC | Significance |
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Study #1 | 36 | 0.80 ± 0.31 | --- | 0.47 ± 0.23 | --- | p<0.00001 | Study #2 | 41 | --- | 1.07 ± 0.38 | --- | 0.87 ± 0.37 | p<0.0014 | Baking soda dentifrices showed significantly greater reductions in mean, whole-mouth, plaque scores as compared to silica-based dentifrices without baking soda following a single brushing. Similar results were obtained when different tooth sites and surfaces were analyzed separately. Conclusions: Dentifrices containing 20% and 65% baking soda significantly enhanced plaque removal by brushing when compared to dentifrices without baking soda. Sponsored by The Church & Dwight Co., Inc. | Seq #306 - Malodor, Dentifrice, Rinses 1:45 PM-3:00 PM, Saturday, July 5, 2008 Metro Toronto Convention Centre Exhibit Hall D-E |
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