ABSTRACT: 3492

Effects of 2-Month Dietary Therapy on Periodontal Status

S. UESAKI¹, Y. FUKUZATO¹, H. IMANAKA¹, H. SUIDOU¹, K. YAMAMOTO¹, T. MAKINO¹, S. KAJIWARA², H. SUZUKI², Y. NISHIO³, A. KASHIWAGI³, and G. KING⁴, ¹Sunstar Inc, Takatsuki, Japan, ²Sunstar Foundation for Oral Health Promotion Senri Dental Clinic, Toyonaka, Japan, ³Shiga University of Medical Science, Otsu, Japan, ⁴Harvard Medical School, Boston, MA, USA

Introduction: Not only decrease in caloric intake but also a quality of diet is one of the most important components of dietary therapy. We previously reported the effects of 2-month dietary therapy on postprandial glucose level and blood lipid composition in obesity, diabetes or pre-diabetes diagnosed by oral glucose tolerance test (OGTT).

Objectives: To examine the effects of dietary therapy for 2months on periodontal status in volunteers including obese, diabetes and/or pre-diabetes.

Methods: Subjects (n=20) diagnosed as diabetes or pre-diabetes by OGTT and/or obesity by body mass index >25 consumed the test diets (three daily meals, 30kcal/kg ideal body weight/day) but nothing else for 2months and then consumed the regular diet for 6months. The test diets were composed of brown rice, green vegetable juice, a main dish and 1-3 side dishes consisting of vegetables, soy beans, white fish and/or chicken (Protein/Fat/Carbon=16/22/62). Probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival crevicular fluid (GCF) values and Interleukin-1beta (IL-1beta) in GCF at the sites with PD³4mm at baseline were measured by a single periodontist (baseline, after 2 and 8months), and statistically analyzed (SPSS ver.15.0J). All the subjects did not receive the prophylaxis procedure, including instruction of tooth brushing during all the test periods.

Results: PD, CAL, BOP and GCF value were significantly improved after 2 and 8months compared with the baseline as table showes. IL-1beta in GCF was not significantly changed after 8months.

Table. Change of periodontal clinical parameters

	baseline	after test diet	after family-style diet
PD(mm)	4.41±1.04	3.90±1.48^c	3.73±1.65^c
CAL(mm)	7.39±2.21	6.90±2.47^c	6.84±2.60^c
BOP	0.72±0.45	0.57±0.50^b	0.53±0.50^c
GCF value	83.4±34.3	76.5±32.3^a	67.3±35.9^c
IL-1beta(pg/site)	28.4±25.7	25.3±27.2^a	33.1±33.4

Significant difference, a:p<0.10,b:p<0.05, c:p<0.01 vs. baseline (Wilcoxon's signed rank test)

Conclusion: These findings suggested that such dietary therapy contribute to the reduction of inflammatory responses of periodontal tissue.

Seq #315 - Clinical Research/Systemic Effects of Treatment/Smoking/Dental Hypersensitivity
1:45 PM-3:00 PM, Saturday, July 5, 2008
Metro Toronto Convention Centre Exhibit Hall D-E

Back to the Periodontal Research - Therapy Program