website: 86th General Session & Exhibition of the IADR

ABSTRACT: 1341  

Antimicrobial Activity of Propolis and Chlorexidine over Streptococcus Mutans Strains

M.P. DE LUCA1, J.C. BACHIEGA2, S.K. BUSSADORI3, A.F. MARANGONI3, R.A. MESQUITA-FERRARI2, E. ESP"SITO4, and E.M. SANTOS3, 1UNIVERSIDADE DE MOGI DAS CRUZES, São Sebastião, Brazil, 2Centro Universitário Nove de Julho, São Sebastião, Brazil, 3Centro Universitário Nove de Julho, São Paulo, Brazil, 4Universidade de Mogi das Cruzes, São Sebastião, Brazil

Introduction: The prevention of carie disease has stimulated the researches of alternative substances to control streptococcus mutans. Objectives: Therefore, the aim of this study was to evaluate in vitro the antimicrobial activity of substances composed by propolis, Noplak Max®, Mn Propolis, Mn Propolis Prata e Periogard®. Cereal alcohol was used for the control group. Methods: Materials were diluted, inoculated on agar plate. Known concentrations of antimicrobial agents were placed in cavities excaveted into the agar and placed on the suface of the culture medium. The inhibition halo was measured after 24 hours. In the experimental group (treated with different substances), 3 ága plates were measured and the average value and average error were obtained. The data was submitted to statistical test Anova Tukey wiht a significance level of p≤ 5%. Results: The results demonstrated that the group treated with Mn Propolis Prata showed the largest inhibition halo against the Streptococcus mutans strains, and the group treated with Periogard® showed the smallest inhibition halo. the control group did not show inhibition halo. Conclusions: This result allows us to conclude that all tested substances presented antimicrobial activity against the Streptococcus mutans strains. Nevertheless, the tests used and the sample size did not allow us to identify statistically which substance is more effective against this strain.

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