website: 86th General Session & Exhibition of the IADR
Seq #137 Friday, July 4, 2008

9:00 AM-10:30 AM
Metro Toronto Convention Centre Room 718B, Symposium - Group/Division Sponsored
Biomechanical Response and Control at the Bone-Biomaterial Interface

Sponsored by: Implantology Research, Oral & Maxillofacial Surgery, Prosthodontics Research, Japan Prosthodontic Society
Description: Reconstructive and regenerative treatments in dental and craniofacial areas largely involve force-sensing and –response at cellular and tissue levels. Particularly, there has been a critical gap in understanding the biomechanical interaction, communication and control at cell/tissue and biomaterial interface. The symposium will cover the topics on 1) mechano-sensing and -response of bone tissue by regulating osteoblastic and osteoclastic function; 2) roles of extracellular matrix and intra-cellular signaling pathway in mechanotransduction; 3) implant surface-mediated biomechanical regulation of osteoblastic differentiation. We will discuss the specificity of cell responses to different types and levels of mechanical stress and force, and how this is significant and relevant to clinical and biological phenomena, and also attempt to link the mechano-response to positive generative/regenerative or pathological states of bone. Researchers from multiple fields, prosthodontic research, implant research, oral surgery, bone biology, and material science, are anticipated to attend this symposium. Supported by Prosthodontics Research Group and Japan Prosthodontic Society.
Chairperson: K. SASAKI
 
1462    Mechanobiological Regulation of Progenitor Cells
C. SIMMONS, University of Toronto, Canada
    Osteoblastic Response to Titanium-mediated Mechanical Stimulation
T. OGAWA, University of California Los Angeles, USA
    Mechanobiology of Osteoblasts and Osteoclasts
M. NODA, Tokyo Medical and Dental University, Japan
    Chronological Sequence of Bone Turn-over Activity Induced by Mechanical Stress
K. SASAKI, Tohoku University, Sendai, Japan
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