SESSION Seq #161: Can We Promote Cementogenesis to Facilitate Periodontal Regeneration

Seq #161

Friday, July 4, 2008

10:45 AM-12:15 PM
Metro Toronto Convention Centre Room 718A, Symposium - Group/Division Sponsored

Can We Promote Cementogenesis to Facilitate Periodontal Regeneration

Sponsored by: Mineralized Tissue, Periodontal Research

Description: Periodontal diseases are high prevalence infections that cause destruction of the supporting tissues of the teeth. A critical stumbling block for improving periodontal health is our inability to reproducibly regenerate the cementum-periodontal interface. We hope to improve understanding of the structural, developmental and cell biologies of root surface cementum in the context of periodontal regeneration. We have aimed this symposium at scientists with a strong background in cell and molecular biology and with a particular interest in periodontology and mineralized tissue formation. We expect that M.Sc. and PhD. students, as well as principal investigators, will benefit from these presentations. Combined with exciting data on new approaches for cementogenesis, we hope to provide attendees with an improved understanding of the biology of cementum and the potential for tissue engineering in promoting cementogenesis. Collectively, these presentations should stimulate fresh thinking on the healing potential of periodontal tissues. Our objectives are: 1) To summarize available knowledge obtained from cell culture, animal models and human studies; 2) To discuss critical knowledge gaps in cementogenesis, particularly as it relates to periodontal regeneration; and 3) To identify key research questions that will pave the way for development of novel procedures to promote cementum formation and periodontal reattachment. Dieter Bosshardt, a renowned Swiss expert on cementum structure, will explain the remarkable variations of structure and organization of different types of cementum and how this heterogeneity impacts function. Bernhard Ganss is a Canadian molecular biologist who will describe the molecular controls that lead to the origin and development of cementum-producing cells. Mark Bartold, an eminent Australian periodontal researcher, will illustrate the great strides made in the application of tissue engineering principles to cementogenesis. Martha Somerman, an American and world leader in cementoblast physiology, will detail cementoblast gene expression and how it can be modulated to promote periodontal regeneration. Supported by Canadian Institutes of Health Research.

Chairperson: C.A. MCCULLOCH


	1576		Structural Heterogeneity of Cementum D. BOSSHARDT, University of Bern, Bern 10, Switzerland
			Do the Development and Origin of Cementum-producing Cells Impact Periodontal Regeneration B. GANSS, University of Toronto, Canada
			Cementum Tissue Engineering - Fact or Fiction P.M. BARTOLD, University of Adelaide, Australia
			Can Cemetoblast Gene Expression be Regulated to Mediate Periodontal Regeneration? M. SOMERMAN, University of Washington, Seattle, USA

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