Evalue Socket Repair with Plasma Rich and Poor in Platelets

(1) Purpose: The purpose of the present study is to compare, through histological evaluation, the bone repair generated 28 days after filling human dental alveoli with platelet-rich plasma (PRP), platelet-poor plasma (PPP) or in a natural way through blood clotting (control), immediately after dental extractions carried out on the same dental arches.

(2) Materials and method: The parameters for bone repair employed were the rate of neovascularization and of fibrosis, the osteoblast activity and the presence of immature or lamellar bone tissue, to which scores zero-to-three were given according to the increasing rate of occurrence.

(3) Results: From among the five parameters analyzed, PRP showed the best results in neovascularization (p=0.0255) and osteoblast/osteoclast activity (p<0.01). There was no significant difference among the five parameters when bone formation was compared either in PPP-filled or control socket.

(4) Conclusion: In short, as far as clotting is concerned, in the 28-days period, PRP is effective in accelerating bone repair of dental socket, while PPP does not change the rate of that restoring.